BDBM50295954 2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-((1-methyl-2-(S)-pyrrolidinyl)methoxy)pyridine::CHEMBL563479

SMILES CN1CCC[C@H]1COc1cnc(Cl)c(OCc2ccnc(F)c2)c1

InChI Key InChIKey=QECSLNSAYMSPEK-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50295954   

TargetNeuronal acetylcholine receptor subunit alpha-2(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50295954(2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  0.0220nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50295954(2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  0.0620nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50295954(2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50295954(2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50295954(2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50295954(2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed