BDBM50295946 7-{[4-(4-Fluorophenyl)piperazin-1-yl]methyl}-3-methyl-2-pyrrolidin-1-yl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL559399

SMILES Cn1c(nc2c(CN3CCN(CC3)c3ccc(F)cc3)c[nH]c2c1=O)N1CCCC1

InChI Key InChIKey=SIMWCYPGUODYMF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50295946   

TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander-Universit£T

Curated by ChEMBL
LigandPNGBDBM50295946(7-{[4-(4-Fluorophenyl)piperazin-1-yl]methyl}-3-met...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]SCH23390 from bovine dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-Universit£T

Curated by ChEMBL
LigandPNGBDBM50295946(7-{[4-(4-Fluorophenyl)piperazin-1-yl]methyl}-3-met...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander-Universit£T

Curated by ChEMBL
LigandPNGBDBM50295946(7-{[4-(4-Fluorophenyl)piperazin-1-yl]methyl}-3-met...)
Affinity DataKi:  630nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-Universit£T

Curated by ChEMBL
LigandPNGBDBM50295946(7-{[4-(4-Fluorophenyl)piperazin-1-yl]methyl}-3-met...)
Affinity DataKi:  840nMAssay Description:Displacement of [3H]SCH23390 from human cloned dopamine D2 long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed