BDBM50295890 CHEMBL558246::N-(4-(N-(3,4-dimethylisoxazol-5-yl)sulfamoyl)phenyl)-2-(5,6-diphenyl-1,2,4-triazin-3-ylthio)acetamide

SMILES Cc1noc(NS(=O)(=O)c2ccc(NC(=O)CSc3nnc(-c4ccccc4)c(n3)-c3ccccc3)cc2)c1C

InChI Key InChIKey=UEEYGKPNWTWNBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295890   

TargetReplicative DNA helicase(Staphylococcus aureus)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50295890(N-(4-(N-(3,4-dimethylisoxazol-5-yl)sulfamoyl)pheny...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed