BDBM50295700 CHEMBL550448::[4-(3-Amino-propoxy)-benzyl]-(6-phenoxy-benzothiazol-2-yl)-amine

SMILES NCCCOc1ccc(CNc2nc3ccc(Oc4ccccc4)cc3s2)cc1

InChI Key InChIKey=FDWQUIRYUSZBIN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50295700   

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rat)
Csiro Molecular and Health Technologies

Curated by ChEMBL
LigandPNGBDBM50295700([4-(3-Amino-propoxy)-benzyl]-(6-phenoxy-benzothiaz...)
Affinity DataEC50:  7.60E+4nMAssay Description:Inhibition of rat neuronal Cav2.2 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50295700([4-(3-Amino-propoxy)-benzyl]-(6-phenoxy-benzothiaz...)
Affinity DataIC50: 2.18E+5nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Iitb-Monash Research Academy

Curated by ChEMBL
LigandPNGBDBM50295700([4-(3-Amino-propoxy)-benzyl]-(6-phenoxy-benzothiaz...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed