BDBM50295645 (1'S,2R,2'S,6'R,9'R)-9'-(4-methoxyphenyl)-6'-methyl-3-methylidene-8'-oxaspiro[oxolane-2,5'-tetracyclo[8.8.0.0^{2,6}.0^{11,16}]octadecane]-10',15'-dien-14'-one::CHEMBL564234

SMILES COc1ccc(cc1)[C@H]1OC[C@@]2(C)[C@@H](CC[C@]22OCCC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12

InChI Key InChIKey=DJRBZWVBECJRTM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295645   

TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50295645((1'S,2R,2'S,6'R,9'R)-9'-(4-methoxyphenyl)-6'-methy...)
Affinity DataIC50: 132nMAssay Description:Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of corticoid-induced transcription after 16 hrs by glucocor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50295645((1'S,2R,2'S,6'R,9'R)-9'-(4-methoxyphenyl)-6'-methy...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed