BDBM50295638 (1S,3S,3aR,3bS,10R)-1-Hydroxy-12a-methyl-10-(4-methylsulfanyl-phenyl)-1-pentafluoroethyl-2,3,3a,3b,4,5,9,10,12,12a-decahydro-1H,8H-11-oxa-naphtho[2,1-e]azulen-7-one::CHEMBL555872

SMILES CSc1ccc(cc1)[C@H]1OC[C@@]2(C)[C@@H](CC[C@@]2(O)C(F)(F)C(F)(F)F)[C@@H]2CCC3=CC(=O)CCC3=C12

InChI Key InChIKey=GCKMJAVBEKTJOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295638   

TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50295638((1S,3S,3aR,3bS,10R)-1-Hydroxy-12a-methyl-10-(4-met...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of corticoid-induced transcription after 16 hrs by glucocor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50295638((1S,3S,3aR,3bS,10R)-1-Hydroxy-12a-methyl-10-(4-met...)
Affinity DataIC50: 56nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed