BDBM50295570 3,4-Dihydro-6,8-dimethyl-3-[2-(6-methylnaphthoyl)]-2H-pyrido[1,2-a]pyrimidine perchlorate::CHEMBL563369

SMILES Cc1cc(C)n2CC(CN[c+]2c1)C(=O)c1ccc2cc(C)ccc2c1

InChI Key InChIKey=RGTRSBQTZKBVSB-UHFFFAOYSA-O

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50295570   

TargetNitric oxide synthase, endothelial(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50295570(3,4-Dihydro-6,8-dimethyl-3-[2-(6-methylnaphthoyl)]...)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50295570(3,4-Dihydro-6,8-dimethyl-3-[2-(6-methylnaphthoyl)]...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioactiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50295570(3,4-Dihydro-6,8-dimethyl-3-[2-(6-methylnaphthoyl)]...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of rat recombinant nNOS expressed in Saccharomyces cerevisiae assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed