BDBM50295525 CHEMBL551590::N-(4-Bromophenyl)-3-[3-(3-methoxybenzyl)-5-methyl-2-oxo-2H-pyridazin-1-yl]-propionamide

SMILES COc1cccc(Cc2cc(C)nn(CCC(=O)Nc3ccc(Br)cc3)c2=O)c1

InChI Key InChIKey=PPOLUASKGNFIRB-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50295525   

TargetfMet-Leu-Phe receptor(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295525(N-(4-Bromophenyl)-3-[3-(3-methoxybenzyl)-5-methyl-...)
Affinity DataEC50:  1.13E+4nMAssay Description:Agonist activity at FPR1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295525(N-(4-Bromophenyl)-3-[3-(3-methoxybenzyl)-5-methyl-...)
Affinity DataEC50:  1.18E+4nMAssay Description:Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295525(N-(4-Bromophenyl)-3-[3-(3-methoxybenzyl)-5-methyl-...)
Affinity DataEC50:  9.70E+3nMAssay Description:Agonist activity at FPR1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295525(N-(4-Bromophenyl)-3-[3-(3-methoxybenzyl)-5-methyl-...)
Affinity DataEC50:  1.18E+4nMAssay Description:Agonist activity at FPRL1 in human neutrophiles by chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295525(N-(4-Bromophenyl)-3-[3-(3-methoxybenzyl)-5-methyl-...)
Affinity DataEC50:  1.13E+4nMAssay Description:Agonist activity at FPR1 in human neutrophiles by chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295525(N-(4-Bromophenyl)-3-[3-(3-methoxybenzyl)-5-methyl-...)
Affinity DataEC50:  5.40E+3nMAssay Description:Agonist activity at FPRL1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed