BDBM50295519 CHEMBL554291::N-(3,4-Dimethoxyphenyl)-2-[5-(3-methoxybenzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-acetamide

SMILES COc1cccc(Cc2cc(C)nn(CC(=O)Nc3ccc(OC)c(OC)c3)c2=O)c1

InChI Key InChIKey=AIJUIYMBFKWGDS-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50295519   

TargetfMet-Leu-Phe receptor(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295519(N-(3,4-Dimethoxyphenyl)-2-[5-(3-methoxybenzyl)-3-m...)
Affinity DataEC50:  1.55E+4nMAssay Description:Agonist activity at FPR1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295519(N-(3,4-Dimethoxyphenyl)-2-[5-(3-methoxybenzyl)-3-m...)
Affinity DataEC50:  1.68E+4nMAssay Description:Agonist activity at FPRL1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295519(N-(3,4-Dimethoxyphenyl)-2-[5-(3-methoxybenzyl)-3-m...)
Affinity DataEC50:  3.60E+3nMAssay Description:Agonist activity at FPR1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295519(N-(3,4-Dimethoxyphenyl)-2-[5-(3-methoxybenzyl)-3-m...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295519(N-(3,4-Dimethoxyphenyl)-2-[5-(3-methoxybenzyl)-3-m...)
Affinity DataEC50:  3.60E+3nMAssay Description:Agonist activity at FPR1 in human neutrophiles by chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50295519(N-(3,4-Dimethoxyphenyl)-2-[5-(3-methoxybenzyl)-3-m...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at FPRL1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed