BDBM50295479 (S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,d]furan-3-sulfonamido)butanoic Acid::CHEMBL550038

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(cc21)N1CCOC1=O)C(O)=O

InChI Key InChIKey=FWPVXLYOKAOERT-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50295479   

LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of human Aggrecanase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 318nMAssay Description:Inhibition of human MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of human MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human Aggrecanase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 7.83E+3nMAssay Description:Inhibition of human MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 66nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 5.46E+3nMAssay Description:Inhibition of human MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 72nMAssay Description:Inhibition of rat MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 27nMAssay Description:Inhibition of mouse MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 106nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295479((S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed