BDBM50295388 (2R)-4-(3-Fluoro-4-(4-(4-fluoro-2-(trifluoromethyl)phenyl)-2-methylpiperazin-1-ylsulfonyl)phenyl)morpholine::CHEMBL559465

SMILES C[C@@H]1CN(CCN1S(=O)(=O)c1ccc(cc1F)N1CCOCC1)c1ccc(F)cc1C(F)(F)F

InChI Key InChIKey=RJHPFQXASHHUEK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50295388   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295388((2R)-4-(3-Fluoro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295388((2R)-4-(3-Fluoro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295388((2R)-4-(3-Fluoro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50: 32nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed