BDBM50295296 CHEMBL539470::cis-3-((1R,2S)-2-((dimethylamino)methyl)cyclopentyl)-1H-indole-5-carbonitrile

SMILES CN(C)C[C@H]1CCC[C@H]1c1c[nH]c2ccc(cc12)C#N

InChI Key InChIKey=RXJIAQGHWRMBEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295296   

TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50295296(cis-3-((1R,2S)-2-((dimethylamino)methyl)cyclopenty...)
Affinity DataIC50: 130nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50295296(cis-3-((1R,2S)-2-((dimethylamino)methyl)cyclopenty...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed