BDBM50295279 2-(2-(2,6-difluorophenylamino)phenyl)acetic acid::CHEMBL260968

SMILES OC(=O)Cc1ccccc1Nc1c(F)cccc1F

InChI Key InChIKey=KHNKXTYWNSVJPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295279   

TargetInterleukin-8(Human)
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50295279(2-(2-(2,6-difluorophenylamino)phenyl)acetic acid |...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50295279(2-(2-(2,6-difluorophenylamino)phenyl)acetic acid |...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of purified mouse COX-2 assessed as inhibition of PGE2-G/PGD2-G formation preincubated for 3 mins before 2-AG substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed