BDBM50294843 (S)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-5-yl)-methanone::CHEMBL556269

SMILES CCCN(CCN1CCN(CC1)C(=O)c1ccc2[nH]ccc2c1)[C@H]1CCc2c(O)cccc2C1

InChI Key InChIKey=HMYBAZWTOQSPCY-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50294843   

TargetD(2) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294843((S)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataEC50:  41.2nMAssay Description:Activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294843((S)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataEC50:  1.23nMAssay Description:Activity at human dopamine D3 receptor expressed in AtT cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294843((S)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi:  2.27nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50294843((S)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi:  157nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed