BDBM50294827 4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-en-4-yl)-cyclohexanecarboxylic acid quinolin-8-ylamide::CHEMBL564783

SMILES O=C(Nc1cccc2cccnc12)[C@H]1CC[C@@H](CC1)N1C(=O)[C@H]2[C@@H]3C[C@@H](C=C3)[C@H]2C1=O

InChI Key InChIKey=HWBJWUBGNFSNFM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294827   

TargetProto-oncogene Wnt-3(Human)
The University of Texas Southwestern Medical Center At Dallas

Curated by ChEMBL
LigandPNGBDBM50294827(4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...)
Affinity DataEC50:  400nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed