BDBM50294802 CHEMBL561779::N-(2,4-Dichloro-phenyl)-4-((1R,2S,6R,7S)-dioxo-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-en-4-yl)-benzamide

SMILES Oc1c2[C@H]3C[C@H](C=C3)c2c(O)n1-c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1Cl

InChI Key InChIKey=UZRGFNIMVXYVHP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294802   

TargetProto-oncogene Wnt-3(Human)
The University of Texas Southwestern Medical Center At Dallas

Curated by ChEMBL
LigandPNGBDBM50294802(N-(2,4-Dichloro-phenyl)-4-((1R,2S,6R,7S)-dioxo-4-a...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed