BDBM50294603 1-(2-(5-(4-methoxybenzyl)-1-((6-methoxypyridin-3-yl)methyl)-4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazin-2-ylamino)ethyl)guanidine::CHEMBL559719

SMILES [#6]-[#8]-c1ccc(-[#6]-n2c(=O)nc(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])n(-[#6]-c3ccc(-[#8]-[#6])nc3)c2=O)cc1

InChI Key InChIKey=PIFNOZWLUDHMJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294603   

TargetProkineticin receptor 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50294603(1-(2-(5-(4-methoxybenzyl)-1-((6-methoxypyridin-3-y...)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed