BDBM50294550 3-Methyl-5-phenethyl-5,6,7,12-tetrahydro-2H-2,5,12-triaza-dibenzo[a,e]azulen-1-one::CHEMBL564365

SMILES Cc1cc2N(CCc3ccccc3)CCc3c([nH]c4ccccc34)-c2c(=O)[nH]1

InChI Key InChIKey=BWGKFZUZSRUEHZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50294550   

TargetInsulin receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294550(3-Methyl-5-phenethyl-5,6,7,12-tetrahydro-2H-2,5,12...)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of human recombinant IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294550(3-Methyl-5-phenethyl-5,6,7,12-tetrahydro-2H-2,5,12...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of 6xHis-tagged human NPM-ALK expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294550(3-Methyl-5-phenethyl-5,6,7,12-tetrahydro-2H-2,5,12...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of recombinant IGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294550(3-Methyl-5-phenethyl-5,6,7,12-tetrahydro-2H-2,5,12...)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of recombinant JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50294550(3-Methyl-5-phenethyl-5,6,7,12-tetrahydro-2H-2,5,12...)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed