BDBM50294162 (R)-(4-(pyrrolidin-2-ylmethoxy)phenyl)(4-(thiophen-3-yl)phenyl)methanone::CHEMBL561639::{4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen-3-ylphenyl)methanone

SMILES c1cc(ccc1c2ccsc2)C(=O)c3ccc(cc3)OC[C@H]4CCCN4

InChI Key InChIKey=VUWFJUJWAWMRQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294162   

TargetLeukotriene A-4 hydrolase(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50294162({4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen...)
Affinity DataIC50: 189nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50294162({4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen...)
Affinity DataIC50: 81nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed