BDBM50294132 CHEMBL561963::N-hydroxy-2-(N-isopropoxy-4'-isopropylbiphenyl-4-ylsulfonamido)-3-methylbutanamide

SMILES CC(C)ON(C(C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(cc1)C(C)C

InChI Key InChIKey=UMEYNLZNXJZVAP-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50294132   

TargetMatrix metalloproteinase-16(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294132(N-hydroxy-2-(N-isopropoxy-4'-isopropylbiphenyl-4-y...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant MMP16More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50294132(N-hydroxy-2-(N-isopropoxy-4'-isopropylbiphenyl-4-y...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294132(N-hydroxy-2-(N-isopropoxy-4'-isopropylbiphenyl-4-y...)
Affinity DataKi:  1nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294132(N-hydroxy-2-(N-isopropoxy-4'-isopropylbiphenyl-4-y...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed