BDBM50294124 2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-N-hydroxyacetamide::CHEMBL550350

SMILES CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccc(Cl)cc2)cc1

InChI Key InChIKey=DKTYDWAJILHINP-UHFFFAOYSA-N

Data  1 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50294124   

Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50: 40nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50: 19nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50: 19nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-16(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant MMP16More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataKi:  25nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed