BDBM50293993 (E)-3-(2-(Purin-9-yl)vinyl)-4-methyl-N-(4-(trifluoromethyl)pyridin-2-yl)benzamide::CHEMBL550281

SMILES Cc1ccc(cc1\C=C\n1cnc2cncnc12)C(=O)Nc1cc(ccn1)C(F)(F)F

InChI Key InChIKey=KILAESXRGZQREB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293993   

TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293993((E)-3-(2-(Purin-9-yl)vinyl)-4-methyl-N-(4-(trifluo...)
Affinity DataIC50: 38nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293993((E)-3-(2-(Purin-9-yl)vinyl)-4-methyl-N-(4-(trifluo...)
Affinity DataIC50: 307nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed