BDBM50293988 (R)-4-(1-Cyclopropylethyl)-6-[6-methoxy-2-(trifluoromethyl)pyridin-3-ylamino]-5-oxo-4,5-dihydropyrazine-2-carbonitrile::CHEMBL563652

SMILES COc1ccc(Nc2nc(cn([C@H](C)C3CC3)c2=O)C#N)c(n1)C(F)(F)F

InChI Key InChIKey=ZGYODANIQNAQIN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293988   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293988((R)-4-(1-Cyclopropylethyl)-6-[6-methoxy-2-(trifluo...)
Affinity DataIC50: 6.70nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed