BDBM50293987 (R)-1-(1-Cyclopropylethyl)-3-[6-methoxy-2-(trifluoromethyl)pyridin-3-ylamino]-5-methylpyrazin-2(1H)-one::CHEMBL559765

SMILES COc1ccc(Nc2nc(C)cn([C@H](C)C3CC3)c2=O)c(n1)C(F)(F)F

InChI Key InChIKey=HQLYOMBBYKTPBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293987   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293987((R)-1-(1-Cyclopropylethyl)-3-[6-methoxy-2-(trifluo...)
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed