BDBM50293968 (S)-5-Chloro-3-(4-methoxy-2,5-dimethylphenylamino)-1-(2-methoxy-1-methylethyl)pyrazin-2(1H)-one::CHEMBL560827

SMILES COC[C@H](C)n1cc(Cl)nc(Nc2cc(C)c(OC)cc2C)c1=O

InChI Key InChIKey=QRGCYSHRQBEQSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293968   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293968((S)-5-Chloro-3-(4-methoxy-2,5-dimethylphenylamino)...)
Affinity DataIC50: 5.80nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed