BDBM50293926 5-Chloro-3-[2,6-dichloro-4-(trifluoromethyl)phenylamino]-1-[2-methoxy-1-(methoxymethyl)ethyl]pyrazin-2(1H)-one::CHEMBL561757

SMILES COCC(COC)n1cc(Cl)nc(Nc2c(Cl)cc(cc2Cl)C(F)(F)F)c1=O

InChI Key InChIKey=FYQWKRTVYNNEHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293926   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293926(5-Chloro-3-[2,6-dichloro-4-(trifluoromethyl)phenyl...)
Affinity DataIC50: 8.5nMAssay Description:Displacement of [125I]ovine-CRF from CRF1 receptor in rat frontal cortex by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed