BDBM50293921 (R)-3,5-Dichloro-4-[6-chloro-4-(2-methoxy-1-methylethyl)-3-oxo-3,4-dihydropyrazin-2-ylamino]benzonitrile::CHEMBL563819

SMILES COC[C@@H](C)n1cc(Cl)nc(Nc2c(Cl)cc(cc2Cl)C#N)c1=O

InChI Key InChIKey=BJPKLUWKFANWNW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293921   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293921((R)-3,5-Dichloro-4-[6-chloro-4-(2-methoxy-1-methyl...)
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]ovine-CRF from CRF1 receptor in rat frontal cortex by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed