BDBM50293673 CHEMBL550825::N2-methyl-N4-(5-methyl-1H-pyrazol-3-yl)-N2-phenylquinazoline-2,4-diamine

SMILES CN(c1ccccc1)c1nc(Nc2cc(C)n[nH]2)c2ccccc2n1

InChI Key InChIKey=HVHBXBDAWFYVOJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293673   

TargetAurora kinase A(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293673(N2-methyl-N4-(5-methyl-1H-pyrazol-3-yl)-N2-phenylq...)
Affinity DataKi:  17nMAssay Description:Inhibition of Aurora-A by coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293673(N2-methyl-N4-(5-methyl-1H-pyrazol-3-yl)-N2-phenylq...)
Affinity DataKi:  312nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293673(N2-methyl-N4-(5-methyl-1H-pyrazol-3-yl)-N2-phenylq...)
Affinity DataKi:  1.06E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed