BDBM50293593 4-(2-aminothiazol-4-yl)benzene-1,3-diol::CHEMBL541251

SMILES Nc1nc(cs1)-c1ccc(O)cc1O

InChI Key InChIKey=JWBRZKPADMMQTN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293593   

TargetFructose-1,6-bisphosphatase 1(Pig)
Boston College

Curated by ChEMBL
LigandPNGBDBM50293593(4-(2-aminothiazol-4-yl)benzene-1,3-diol | CHEMBL54...)
Affinity DataIC50: 9.30E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTyrosinase(Human)
Universite Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50293593(4-(2-aminothiazol-4-yl)benzene-1,3-diol | CHEMBL54...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of human tyrosinase using L- DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetTyrosinase(Human)
Universite Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50293593(4-(2-aminothiazol-4-yl)benzene-1,3-diol | CHEMBL54...)
Affinity DataEC50:  51nMAssay Description:Inhibition of human his tagged tyrosinase expressed in HEK293 cells using L-DOPA as substrate incubated for 10 mins by microtitre plate reader analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed