BDBM50293592 4-(2-Aminothiazol-4-yl)phenol::4-(2-amino-1,3-thiazol-4-yl)phenol::CHEMBL483790

SMILES Nc1nc(cs1)-c1ccc(O)cc1

InChI Key InChIKey=QGSJYYIRAFRPIT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50293592   

TargetLeukotriene A-4 hydrolase(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50293592(4-(2-amino-1,3-thiazol-4-yl)phenol | 4-(2-Aminothi...)
Affinity DataIC50: 1.44E+6nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Boston College

Curated by ChEMBL
LigandPNGBDBM50293592(4-(2-amino-1,3-thiazol-4-yl)phenol | 4-(2-Aminothi...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50293592(4-(2-amino-1,3-thiazol-4-yl)phenol | 4-(2-Aminothi...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50293592(4-(2-amino-1,3-thiazol-4-yl)phenol | 4-(2-Aminothi...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50293592(4-(2-amino-1,3-thiazol-4-yl)phenol | 4-(2-Aminothi...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed