BDBM50293168 4-(2-ethylpyrazolo[1,5-b]pyridazin-3-yl)-N-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine::CHEMBL496360

SMILES CCc1nn2ncccc2c1-c1ccnc(Nc2ccc(cc2)N2CCN(C)CC2)n1

InChI Key InChIKey=RBIONWHBBUZDRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293168   

TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293168(4-(2-ethylpyrazolo[1,5-b]pyridazin-3-yl)-N-(4-(4-m...)
Affinity DataIC50: 63nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293168(4-(2-ethylpyrazolo[1,5-b]pyridazin-3-yl)-N-(4-(4-m...)
Affinity DataIC50: 25nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed