BDBM50293167 CHEMBL524086::N-(4-(4-methylpiperazin-1-yl)phenyl)-4-(2-methylpyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine

SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2c(C)nn3ncccc23)cc1

InChI Key InChIKey=RRUGSPOGOGBMMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293167   

TargetVascular endothelial growth factor receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293167(N-(4-(4-methylpiperazin-1-yl)phenyl)-4-(2-methylpy...)
Affinity DataIC50: 63nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293167(N-(4-(4-methylpiperazin-1-yl)phenyl)-4-(2-methylpy...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed