BDBM50293155 CHEMBL497564::N-(3-(oxazol-4-yl)phenyl)-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine

SMILES N(c1cccc(c1)-c1cocn1)c1nccc(n1)-c1cnn2ncccc12

InChI Key InChIKey=AKEMXASAMBDUOC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293155   

TargetCyclin-dependent kinase 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293155(N-(3-(oxazol-4-yl)phenyl)-4-(pyrazolo[1,5-b]pyrida...)
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293155(N-(3-(oxazol-4-yl)phenyl)-4-(pyrazolo[1,5-b]pyrida...)
Affinity DataIC50: 8nMAssay Description:Inhibition of GSK3-beta by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293155(N-(3-(oxazol-4-yl)phenyl)-4-(pyrazolo[1,5-b]pyrida...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CDK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed