BDBM50293139 CHEMBL496778::N-cyclopentyl-3-(2-(cyclopropylamino)pyrimidin-4-yl)pyrazolo[1,5-b]pyridazin-6-amine

SMILES C1CC1Nc1nccc(n1)-c1cnn2nc(NC3CCCC3)ccc12

InChI Key InChIKey=LTNXNHHGQLANQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293139   

TargetCyclin-dependent kinase 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293139(N-cyclopentyl-3-(2-(cyclopropylamino)pyrimidin-4-y...)
Affinity DataIC50: 160nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293139(N-cyclopentyl-3-(2-(cyclopropylamino)pyrimidin-4-y...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of GSK3-beta by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed