BDBM50293136 4-Chloro-17-Azapentacycle[6.6.5.0(2,7).0(9,14).0(15,19)]nonadeca-2,4,6,9(14),10,12-hexen-16,18-dione::CHEMBL475745

SMILES Clc1ccc2C3C4C(C(c5ccccc35)c2c1)C(=O)NC4=O

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293136   

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Mouse)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50293136(4-Chloro-17-Azapentacycle[6.6.5.0(2,7).0(9,14).0(1...)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of mouse brain L-type Cav1.2 channel by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50293136(4-Chloro-17-Azapentacycle[6.6.5.0(2,7).0(9,14).0(1...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50293136(4-Chloro-17-Azapentacycle[6.6.5.0(2,7).0(9,14).0(1...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed