BDBM50293110 2-(4-Fluorophenyl)-6-methoxybenzo[d]thiazole::6-Methoxy-2-(4'-fluorophenyl)-1,3-benzothiazole::CHEMBL490083

SMILES COc1ccc2nc(sc2c1)-c1ccc(F)cc1

InChI Key InChIKey=FFMONRZWRJLZNE-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293110   

TargetLuciferin 4-monooxygenase(Pennsylania firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50293110(2-(4-Fluorophenyl)-6-methoxybenzo[d]thiazole | 6-M...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by competitive KinaseGlo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Pennsylania firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50293110(2-(4-Fluorophenyl)-6-methoxybenzo[d]thiazole | 6-M...)
Affinity DataIC50: 860nMAssay Description:Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by competitive inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50293110(2-(4-Fluorophenyl)-6-methoxybenzo[d]thiazole | 6-M...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of luciferin binding site of Photinus pyralis luciferase by competitive inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Katholieke Universiteit Leuven

Curated by ChEMBL
LigandPNGBDBM50293110(2-(4-Fluorophenyl)-6-methoxybenzo[d]thiazole | 6-M...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [125I]IMPY from beta-amyloid plaques in Alzheimer's disease patient brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed