BDBM50293009 2-Amino-4-(4-methoxyphenyl)-7-(phenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile::CHEMBL451114

SMILES COc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1

InChI Key InChIKey=BELJXBUHMMFZFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293009   

TargetExcitatory amino acid transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50293009(2-Amino-4-(4-methoxyphenyl)-7-(phenyl)-5-oxo-5,6,7...)
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50293009(2-Amino-4-(4-methoxyphenyl)-7-(phenyl)-5-oxo-5,6,7...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50293009(2-Amino-4-(4-methoxyphenyl)-7-(phenyl)-5-oxo-5,6,7...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed