BDBM50293005 2-amino-5-oxo-7-phenyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile::CHEMBL460701

SMILES N=C1OC2=C(C(C1C#N)c1cccs1)C(=O)CC(C2)c1ccccc1

InChI Key InChIKey=VQBVDCARHJOXOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293005   

TargetExcitatory amino acid transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50293005(2-amino-5-oxo-7-phenyl-4-(thiophen-2-yl)-5,6,7,8-t...)
Affinity DataIC50: 1.40E+4nMAssay Description:Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50293005(2-amino-5-oxo-7-phenyl-4-(thiophen-2-yl)-5,6,7,8-t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50293005(2-amino-5-oxo-7-phenyl-4-(thiophen-2-yl)-5,6,7,8-t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed