BDBM50293004 2-amino-4-(4-bromothiophen-2-yl)-5-oxo-7-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile::CHEMBL517413

SMILES Brc1csc(c1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1

InChI Key InChIKey=JCCPINXOEIBSHV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293004   

TargetExcitatory amino acid transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50293004(2-amino-4-(4-bromothiophen-2-yl)-5-oxo-7-phenyl-5,...)
Affinity DataIC50: 4.70E+3nMAssay Description:Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50293004(2-amino-4-(4-bromothiophen-2-yl)-5-oxo-7-phenyl-5,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50293004(2-amino-4-(4-bromothiophen-2-yl)-5-oxo-7-phenyl-5,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed