BDBM50292744 1-(Benzylamino)ethaniminium bromide::CHEMBL462334

SMILES C\C(N)=[NH+]\Cc1ccccc1

InChI Key InChIKey=TVGAZFIPLVKCJM-UHFFFAOYSA-O

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50292744   

TargetNitric oxide synthase, inducible(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50: 200nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Università

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50292744(1-(Benzylamino)ethaniminium bromide | CHEMBL462334)
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed