BDBM50292735 CHEMBL514014::N4-(3-bromophenyl)-6-(3,4,5-trimethoxybenzyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

SMILES COc1cc(Cc2cc3c(Nc4cccc(Br)c4)nc(N)nc3[nH]2)cc(OC)c1OC

InChI Key InChIKey=RAHJYUHWGCMOFT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50292735   

TargetEpidermal growth factor receptor(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50292735(N4-(3-bromophenyl)-6-(3,4,5-trimethoxybenzyl)-7H-p...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50292735(N4-(3-bromophenyl)-6-(3,4,5-trimethoxybenzyl)-7H-p...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50292735(N4-(3-bromophenyl)-6-(3,4,5-trimethoxybenzyl)-7H-p...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50292735(N4-(3-bromophenyl)-6-(3,4,5-trimethoxybenzyl)-7H-p...)
Affinity DataIC50: 9.42E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50292735(N4-(3-bromophenyl)-6-(3,4,5-trimethoxybenzyl)-7H-p...)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed