BDBM50292581 CHEMBL4165870

SMILES CCN1CCC[C@@H]1CNC(=O)c1ccc2Sc3c(C)cccc3C(=O)Nc2c1

InChI Key InChIKey=TUAFUWGZCFIOSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292581   

TargetGlucose-6-phosphate 1-dehydrogenase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50292581(CHEMBL4165870)
Affinity DataIC50: 8.00E+4nMAssay Description:Competitive inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by Linew...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2020
Entry Details Article
PubMed
TargetBifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase(Plasmodium falciparum (isolate 3D7))
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50292581(CHEMBL4165870)
Affinity DataIC50: 190nMAssay Description:Competitive inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2020
Entry Details Article
PubMed