BDBM50292389 3-epi-fagomine::3-epifagomine::CHEMBL456583

SMILES OC[C@H]1NCC[C@H](O)[C@@H]1O

InChI Key InChIKey=YZNNBIPIQWYLDM-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50292389   

TargetBeta-galactosidase(Bovine)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 3.10E+3nMAssay Description:Concentration that causes 50% inhibition of mammalian cytosolic beta-galactosidase was determined in bovine liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetBeta-galactosidase(Bovine)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 1.50E+3nMAssay Description:Tested for competitive inhibition of bovine liver beta-galactosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Wistar rat intestinal isomaltase by glucose B-testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Bovine)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetBeta-galactosidase(Bovine)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLactase/phlorizin hydrolase(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLactase/phlorizin hydrolase(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 1.90E+3nMAssay Description:Tested for competitive inhibition of rat intestinal lactaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 5.00E+5nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-glucosidase (maltase) was determined in rat intestineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetNeutral alpha-glucosidase C(Mouse)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 6.40E+3nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-glucosidase (isomaltase) was determined in rat intestineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetBeta-glucosidase A(Caldocellum saccharolyticum)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration that causes 50% inhibition of mammalian cellobiase beta-glucosidase was determined in rat intestineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 1.00E+6nMAssay Description:Concentration that causes 50% inhibition of mammalian alpha-L-fucosidase was determined in bovine epididymisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetBeta-galactosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 4.00E+3nMAssay Description:Concentration that causes 50% inhibition of mammalian lactase beta-galactosidase was determined in rat intestineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50292389(3-epifagomine | 3-epi-fagomine | CHEMBL456583)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed