BDBM50292333 CHEMBL505374::zaragozic acid C

SMILES C[C@H](CCCc1ccccc1)\C=C\CCC(=O)O[C@@H]1[C@@H](O)[C@]2(CCC[C@@H](OC(C)=O)[C@H](C)Cc3ccccc3)O[C@@]1(C(O)=O)[C@@](O)([C@H](O2)C(O)=O)C(O)=O

InChI Key InChIKey=KQMNJFMTGHRJHM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50292333   

TargetSqualene synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50292333(zaragozic acid C | CHEMBL505374)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50292333(zaragozic acid C | CHEMBL505374)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50292333(zaragozic acid C | CHEMBL505374)
Affinity DataKi:  0.0450nMAssay Description:Inhibition of rat squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article