BDBM50291964 CHEMBL4174712

SMILES Cc1cc(cc(C)c1Nc1ccnc(Nc2ccc(cc2)C#N)n1)-c1ccc(cc1)C#N

InChI Key InChIKey=RARAMGIQFJHXBX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291964   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291964BDBM50291964(CHEMBL4174712)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant wild type HIV1 reverse transcriptase p66/p51 using poly (rA)/anoligo (dT)16 as template/primer assessed as inhibition of bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2020
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50291964BDBM50291964(CHEMBL4174712)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant wild type HIV-1 reverse transcriptase incubated for 40 mins in presence of poly(rA) template/oligo(dT)16 primer by Pico-Gre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed