BDBM50291895 CHEMBL4177176

SMILES Clc1ccc(cc1)C(=O)Nc1cccc(CCOc2cccc3C(CCc23)NCC#C)c1

InChI Key InChIKey=FRIUBBKJDOTFNB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50291895   

TargetAmine oxidase [flavin-containing] A(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50291895(CHEMBL4177176)
Affinity DataIC50: 9.33E+3nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured over 15 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50291895(CHEMBL4177176)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured over 15 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50291895(CHEMBL4177176)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed