BDBM50291800 6,6-Dimethyl-1-(3-undecyloxy-phenyl)-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL280726

SMILES CCCCCCCCCCCOc1cccc(c1)N1C(N)=NC(N)=NC1(C)C

InChI Key InChIKey=QPXDTEXOMMULLS-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50291800   

TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50291800(6,6-Dimethyl-1-(3-undecyloxy-phenyl)-1,6-dihydro-[...)
Affinity DataKi:  4.5nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50291800(6,6-Dimethyl-1-(3-undecyloxy-phenyl)-1,6-dihydro-[...)
Affinity DataKi:  18.6nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
TBA

Curated by ChEMBL
LigandPNGBDBM50291800(6,6-Dimethyl-1-(3-undecyloxy-phenyl)-1,6-dihydro-[...)
Affinity DataKi:  275nMAssay Description:Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291800(6,6-Dimethyl-1-(3-undecyloxy-phenyl)-1,6-dihydro-[...)
Affinity DataKi:  646nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
LigandPNGBDBM50291800(6,6-Dimethyl-1-(3-undecyloxy-phenyl)-1,6-dihydro-[...)
Affinity DataKi:  977nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Leishmania majorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed