BDBM50291778 CHEMBL20812::N-{3-[3-(4,6-Diamino-2,2-dimethyl-2H-[1,3,5]triazin-1-yl)-benzyloxy]-phenyl}-acetamide

SMILES CC(=O)Nc1cccc(OCc2cccc(c2)N2C(N)=NC(N)=NC2(C)C)c1

InChI Key InChIKey=WHSVABAIBQNZRR-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50291778   

TargetDihydrofolate reductase(Pneumocystis carinii)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50291778(N-{3-[3-(4,6-Diamino-2,2-dimethyl-2H-[1,3,5]triazi...)
Affinity DataKi:  3.24nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50291778(N-{3-[3-(4,6-Diamino-2,2-dimethyl-2H-[1,3,5]triazi...)
Affinity DataKi:  5.5nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
TBA

Curated by ChEMBL
LigandPNGBDBM50291778(N-{3-[3-(4,6-Diamino-2,2-dimethyl-2H-[1,3,5]triazi...)
Affinity DataKi:  23nMAssay Description:Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
LigandPNGBDBM50291778(N-{3-[3-(4,6-Diamino-2,2-dimethyl-2H-[1,3,5]triazi...)
Affinity DataKi:  75.9nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Leishmania majorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50291778(N-{3-[3-(4,6-Diamino-2,2-dimethyl-2H-[1,3,5]triazi...)
Affinity DataKi:  245nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291778(N-{3-[3-(4,6-Diamino-2,2-dimethyl-2H-[1,3,5]triazi...)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed