BDBM50291708 (S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester::CHEMBL154828

SMILES CCOCCOc1ccc(cc1)[P@@](=O)(OCC)N1Cc2ccccc2C[C@@H]1C(=O)NO

InChI Key InChIKey=SQYRXZTYDRVAMZ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50291708   

TargetMatrix metalloproteinase-9(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291708((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi:  14nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291708((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi:  30nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291708((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi:  573nMAssay Description:Inhibitory constant against recombinant human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291708((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi: >650nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291708((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi: >800nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291708((S)-[4-(2-Ethoxy-ethoxy)-phenyl]-((R)-3-hydroxycar...)
Affinity DataKi: >850nMAssay Description:Inhibitory constant against recombinant human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed