BDBM50291564 CHEMBL418704::{1-[(R)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethylamino]-2-phenyl-ethyl}-phosphonic acid

SMILES OP(O)(=O)C(Cc1ccccc1)N[C@H](Cc1ccc(cc1)-c1ccccc1)c1nnn[nH]1

InChI Key InChIKey=NAOAQOAPOBTFLY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291564   

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291564({1-[(R)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291564({1-[(R)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 17nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article